PhD Student "Translational Cancer Biology" - Klinik für Kinder- und Jugendmedizin

AUFGABEN & PROFIL

BENEFITS

KONTAKT

UNIVERSITÄTSMEDIZIN

EINDRÜCKE

JETZT BEWERBEN

TEILEN

PhD Student “Translational Cancer Biology” - Klinik für Kinder- und Jugendmedizin Anstellungsart: Befristeter Vertrag Arbeitsmodell: Teilzeit Ausschreibungsnummer: 2036237 ...you're in the middle of it We are looking for a highly motivated PhD student to join the translational pediatric oncology research group of Dr. Christian Braun at the Department of Pediatrics (Director: Prof. Jan-Henning Klusmann). Our lab investigates how dysregulated gene expression programs contribute to the development and progression of cancer, with the goal of identifying new therapeutic vulnerabilities. We combine advanced CRISPR-based screening approaches with transcriptomic and proteomic profiling, using patient-derived cancer models to explore the molecular mechanisms that drive high-risk tumors. Your Role: Designing and conducting CRISPR-based genetic screens in cancer models Performing statistical analyses of epigenetic, transcriptomic and proteomic datasets Validating candidate genes and pathways in vitro and in vivo Contributing to the development of targeted therapeutic strategies ... your skills are what we're looking for Master's degree in life sciences or a related field Strong interest in discovering novel therapeutic approaches and understanding epigenetic mechanisms of gene regulation Hands-on experience with standard molecular biology techniques (e.g., cloning, PCR, flow cytometry) Proficiency in bioinformatics and the analysis of high-throughput datasets (e.g., RNA-seq, proteomics) Ability to work both independently and as part of a collaborative research team Excellent communication skills and proficiency in spoken and written English Due to legal regulations, valid proof of measles immunity / measles vaccination is required ... you'll be offered a lot The position (65% - E 13 ) is initially limited for 2 years with the possibility for extension Excellent scientific environment & dedicated mentoring Participation in training and qualification programs of the MSNZ and the Goethe University Training in novel cutting edge techniques to study epigenetic mechanisms in cancer Collaboration opportunities with national & international world-leading laboratories Free public transport in all Hessen (Free State Ticket Hessen) Uniklinik-Campus, Mensa, Cafés Insights: Instagram , YouTube , LinkedIn FAQ´s for new employees It's time to join our team! Contact: Prof. Dr. Jan-Henning Klusmann Email: [email protected] Application Deadline: 08.08.2025 We welcome applications from candidates of all genders. Applicants with severe disabilities will be given preferential consideration in cases of equal personal and professional qualifications.

JETZT BEWERBEN

… sind Sie mittendrin in der Medizin von morgen Genau hier sind Sie mittendrin in der Medizin von morgen. Die Universitätsmedizin Frankfurt gehört zu den führenden Universitätskliniken in Deutschland. Bei uns ziehen über 8.500 Menschen aus über 100 Nationen an einem Strang. Aus Wissen wird Gesundheit - das ist dabei unser täglicher Antrieb. Denn wir verbinden Krankenversorgung mit Forschung und Lehre , begrüßen den Fortschritt und entwickeln uns selbst immer weiter. So leisten wir einen wichtigen Beitrag für die Gesundheit und die Lebensqualität von über 500.000 Patientinnen und Patienten jährlich: kompetent, gewissenhaft und mit Leidenschaft. › ‹ UNIVERSITÄTSMEDIZIN FRANKFURT | RECRUITING TEAM | THEODOR-STERN-KAI 7 | 60590 FRANKFURT AM MAIN Bitte reichen Sie Ihre Bewerbung ausschließlich über den Button „Jetzt bewerben“ ein. Rückfragen können Sie gerne an [email protected] richten. Bitte beachten Sie, dass keine Unterlagen zurückgeschickt werden. | Folgen Sie uns auf Instagram (@unimedizin_ffm); XING , LinkedIn , Youtube . JETZT BEWERBEN

TEILEN

Designing and conducting CRISPR-based genetic screens in cancer models Performing statistical analyses of epigenetic, transcriptomic and proteomic datasets Validating candidate genes and pathways in vitro and in vivo Contributing to the development of targeted therapeutic strategies Collaboration opportunities with national & international world-leading laboratories Master's degree in life sciences or a related field Strong interest in discovering novel therapeutic approaches and understanding epigenetic mechanisms of gene regulation Hands-on experience with standard molecular biology techniques (e.g., cloning, PCR, flow cytometry) Proficiency in bioinformatics and the analysis of high-throughput datasets (e.g., RNA-seq, proteomics) Ability to work both independently and as part of a collaborative research team Excellent communication skills and proficiency in spoken and written English Due to legal regulations, valid proof of measles immunity / measles vaccination is required